403605-00-5

Upstream product

• 403604-98-8 Benzoic acid (3aS,6S,6aS)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl ester 
• 23262-80-8 2,3,5,6-di-O-isopropylidene-L-gulono-1,4-lactone 
• 7306-64-1 2,3,5,6-di-O-isopropylidene-D-mannono-1,4-lactone 

Downstream Products

• 4099-88-1 2,3-O-isopropylidene-L-ribofuranose 

Relevant academic research and scientific papers

One-pot inversion of D-mannono-1,4-lactone for the practical synthesis of L-ribose

L-Ribose was synthesized in a concise manner from D-mannono-1,4-lactone using one-pot inversion conditions. Treatment of D-mannono-1,4-lactone with piperidine, followed by mesylation-induced SN2-type O-alkylation, afforded the desired one-pot inversion in an optimum yield, and the following straightforward transformations provided L-ribose in good yields.