40361-25-9

Upstream product

• 136983-33-0 2,2,2-Trichloro-acetimidic acid (2S,3S)-3-isopropyl-oxiranylmethyl ester 
• 125414-30-4 (1'S,4R)-4-(2'-methyl-1'-hydroxypropyl)-2-(trichloromethyl)-2-oxazoline 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 40361-27-1 Toluene-4-sulfonic acid (2R,3S)-2-benzyloxycarbonylamino-3-hydroxy-4-methyl-pentyl ester 
• 136898-34-5 4-[(S)-2-Methyl-1-((R)-2-oxo-oxazolidin-4-yl)-propoxy]-benzoic acid tert-butyl ester 
• 136983-36-3 Toluene-4-sulfonic acid (S)-2-methyl-1-((R)-2-oxo-oxazolidin-4-yl)-propyl ester 
• 136898-35-6 4-{(S)-1-[(S)-tert-Butoxycarbonylamino-(2-trimethylsilanyl-ethoxycarbonyl)-methyl]-2-methyl-propoxy}-benzoic acid tert-butyl ester 
• 136898-36-7 4-{(S)-1-[(S)-tert-Butoxycarbonylamino-(2-trimethylsilanyl-ethoxycarbonyl)-methyl]-2-methyl-propoxy}-benzoic acid 
• 136898-39-0 (2S,3S)-3-[4-(2-Amino-1-hydroxy-ethyl)-phenoxy]-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 2-trimethylsilanyl-ethyl ester 
• 25350-22-5 frangulanine 
• 136898-37-8 (2S,3S)-3-[4-(2-Benzyloxycarbonyl-acetyl)-phenoxy]-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 2-trimethylsilanyl-ethyl ester 
• 136898-43-6 [(3S,4S,7S)-7-Isobutyl-3-isopropyl-11-(4-nitro-phenylselanyl)-5,8-dioxo-2-oxa-6,9-diaza-bicyclo[10.2.2]hexadeca-1⁽¹⁵⁾,12⁽¹⁶⁾,13-trien-4-yl]-carbamic acid tert-butyl ester 
• 214900-85-3 (2S,3S)-3-{4-[2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-1-hydroxy-ethyl]-phenoxy}-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 
• 136898-38-9 (2S,3S)-3-(4-{2-Benzyloxycarbonyl-2-[(Z)-hydroxyimino]-acetyl}-phenoxy)-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 2-trimethylsilanyl-ethyl ester 
• 136897-84-2 (2S,3S)-3-{4-[2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-1-hydroxy-ethyl]-phenoxy}-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid 2-trimethylsilanyl-ethyl ester 
• 214900-86-4 (2S,3S)-3-{4-[2-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-1-hydroxy-ethyl]-phenoxy}-2-tert-butoxycarbonylamino-4-methyl-pentanoic acid pentafluorophenyl ester 

Relevant academic research and scientific papers

STEREODIVERGENT SYNTHESIS OF OPTICALLY ACTIVE AMINO ALCOHOLS FROM ASYMMETRISED TRIS(HYDROXYMETHYL)METHANE (THYM)

Degradation of a side arm of the chiral building block asymmetrised bis(hydroxymethyl)methane (THYM*) to give an amino group (CH2OH -> NH2) establishes the synthetic equivalence of THYM* (latent symmetry C3V) with serinol (latent symmetry Csub

The Total Synthesis of Frangulanine

The reported preparation of the p-ansa compound frangulanine, previously isolated from Rhamnus frangula L., also constitutes the first total synthesis of a fourteen-membered cyclopeptide alkaloid.