403640-27-7Relevant academic research and scientific papers
5-(2,6-Difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1, 2-isoxazoline as a useful rice herbicide
In, Taek Hwang,Hyoung, Rae Kim,Dong, Ju Jeon,Kyung, Sik Hong,Jong, Hwan Song,Kwang, Yun Cho
, p. 8639 - 8643 (2005)
5-(2,6-Difluorobenzyl)oxymethyl-5-methyl-3-(3-methylthiophen-2-yl)-1, 2-isoxazoline derivative was synthesized, and its herbicidal activity was assessed under glasshouse and flooded paddy conditions. 5-(2,6-Difluorobenzyl) oxymethyl-5-methyl-3-(3-methylth
Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization
Lee, Hyo-Jun,Eun, Bora,Sung, Eonseon,Hwang, Gil Tae,Ko, Young Kwan,Cho, Chang-Woo
, p. 657 - 664 (2018/02/07)
An efficient quinidine-based phase-transfer-catalyzed enantioselective cascade oxa-Michael-cyclization reaction of hydroxylamine with various β-carboxy-substituted α,β-unsaturated ketones has been achieved for the preparation of chiral carboxy-substituted 2-isoxazolines. This cascade reaction provided the desired products in good yields (up to 98%) with excellent enantioselectivities (91-96% ee). In addition, the cascade reaction was effectively applied to the first catalytic asymmetric synthesis of the herbicide (S)-methiozolin.
INDUSTRIAL METHOD FOR MANUFACTURING HIGH-PURITY METHIOZOLINE
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Paragraph 0030, (2015/02/25)
Provided is an industrial method for the preparation of [5-{(2,6-difluorobenzyloxy)methyl}-4,5-dihydro-5-methyl-3-(3-methylthiophene-2-yl)-isoxazole] (common name: methiozolin) represented by Formula 1 that is a herbicidal substance in high-purity.
INDUSTRIAL METHOD FOR THE PREPARATON OF HIGH-PURITY METHIOZOLIN
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Paragraph 0028; 0030, (2015/06/17)
Provided is an industrial method for the preparation of [5-{(2,6-difluorobenzyloxy)methyl}-4,5-dihydro-5-methyl-3-(3-methylthiophene-2-yl)-isoxazole](common name: methiozolin) represented by Formula 1 that is a herbicidal substance in high-purity.
