403657-24-9Relevant academic research and scientific papers
Synthesis of 5-Pyridyl-2-furaldehydes via palladium-catalyzed cross-coupling with triorganozincates
Gauthier Jr., Donald R.,Szumigala Jr., Ronald H.,Dormer, Peter G.,Armstrong III, Joseph D.,Volante,Reider, Paul J.
, p. 375 - 378 (2002)
(Equation Presented) 5-Pyridyl-and 5-aryl-2-furaldehydes are prepared from furaldehyde diethyl acetal in a four-step, one-pot procedure: (i) deprotonation; (2) Li to Zn transmetalation; (3) Pd-mediated cross-coupling; (4) aldehyde deprotection. Triorganozincate 7 was found to transfer all three groups in the Pd-catalyzed cross-coupling reaction with haloaromatics.
