403694-62-2

Upstream product

• 165817-41-4 (2S,4R)-4-[(6S)-6-benzyloxyhept-1-enyl]-2-methoxymethoxyhexanedioic acid 6-ethyl ester 1-methyl ester 
• 165817-39-0 (2S,4E,6R,10S)-10-benzyloxy-6-(4-methoxybenzyloxy)-2-methoxymethoxyundec-4-enoic acid methyl ester 
• 165817-38-9 methoxymethoxyacetic acid (1R)-1-[(1R,5S)-5-benzyloxy-1-(4-methoxybenzyloxy)hexyl]allyl ester 
• 165817-36-7 (2R,4E,6S)-6-benzyloxy-2-(4-methoxybenzyloxy)hept-4-enoic acid methyl ester 
• 403694-63-3 (2R,6S)-6-benzyloxy-2-(4-methoxybenzyloxy)heptanoic acid methyl ester 
• 165817-37-8 (3R,4R,8S)-8-benzyloxy-4-(4-methoxybenzyloxy)non-1-en-3-ol 
• 165817-40-3 (2S,4E,6R,10S)-10-benzyloxy-6-hydroxy-2-methoxymethoxyundec-4-enoic acid methyl ester 
• 165817-42-5 (3R,4E,9S)-9-benzyloxy-3-[(2S)-3-hydroxy-2-methoxymethoxypropyl]dec-4-enoic acid ethyl ester 

Downstream Products

• 165817-34-5 (1R,2S,4S)-2-[(1E,6S)-6-benzyloxyhept-1-enyl]-4-methoxymethoxycyclopentanecarboxylic acid ethyl ester 
• 20350-15-6 (+)-brefeldin A 

Relevant academic research and scientific papers

Asymmetric total synthesis of (+)-brefeldin A from (S)-lactate by triple chirality transfer process and nitrile oxide cycloaddition

A novel synthesis of (+)-brefeldin A (1) has been accomplished on the basis of triple chirality transfer methodology, intramolecular ester enolate alkylation, and both intra- and intermolecular nitrile oxide cycloaddition strategies.