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3-Quinolinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-6-cyano- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 403839-05-4 Structure
  • Basic information

    1. Product Name: 3-Quinolinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-6-cyano-
    2. Synonyms:
    3. CAS NO:403839-05-4
    4. Molecular Formula: C19H14ClN3O3
    5. Molecular Weight: 367.791
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 403839-05-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-Quinolinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-6-cyano-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-Quinolinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-6-cyano-(403839-05-4)
    11. EPA Substance Registry System: 3-Quinolinecarboxylic acid, 4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-6-cyano-(403839-05-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 403839-05-4(Hazardous Substances Data)

403839-05-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 403839-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,3,8,3 and 9 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 403839-05:
(8*4)+(7*0)+(6*3)+(5*8)+(4*3)+(3*9)+(2*0)+(1*5)=134
134 % 10 = 4
So 403839-05-4 is a valid CAS Registry Number.

403839-05-4Relevant articles and documents

Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction

Bi, Yingzhi,Stoy, Patrick,Adam, Leonard,He, Bin,Krupinski, John,Normandin, Diane,Pongrac, Ron,Seliger, Laurie,Watson, Andrew,Macor, John E.

, p. 1577 - 1580 (2007/10/03)

In a continuing effort to discover novel chemotypes as potent and selective PDE5 inhibitors for the treatment of male erectile dysfunction (ED), we have found that 4-benzylaminoquinoline derivatives are very potent and selective PDE5 inhibitors. Some compounds in this series had PDE5 IC 50's as low as 50 pM. While an electron withdrawing group at the C6-position of the quinoline substantially improved PDE5 potency, an ethyl group at the C8-position not only improved the PDE5 potency but also the isozyme selectivity. Substitutents at the C3-position can incorporate a variety of different groups. The synthesis and primary structure-activity relationship of this new series of potent PDE5 inhibitors are described.

Quinoline inhibitors of cGMP phosphodiesterase

-

, (2008/06/13)

are useful as inhibitors of cGMP PDE especially Type 5.

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