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• 99-31-0 5-aminoisophthalic acid 
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Relevant academic research and scientific papers

A designed metal-organic framework based on a metal-organic polyhedron

A C3 symmetric ligand with three 1,3-benzenedicarboxylate units has been used to construct a metal-organic framework with a (3,24)-connected network topology, where the nanometre-sized metal-organic cuboctahedra (MOCs) have been incorporated solely into a cubic close packing (CCP) arrangement, which led to superoctahedral and supertetrahedral cavities. The Royal Society of Chemistry.

COMPOSITION FOR FORMING RESIST UNDERLAY FILM

PROBLEM TO BE SOLVED: To provide a dendrimer compound that can improve critical dimension uniformity and a depth of focus margin, and a composition for forming a resist underlay film for electron beam or EUV lithography, from which an underlay film can be formed.SOLUTION: A dendrimer compound comprises an aromatic skeleton as a center and a branched chain including an amide bond or an ester bond and an aromatic skeleton. The composition for forming an underlay film comprises the above compound; and the composition exhibits improvement in sensitivity, exposure latitude, depth of focus, LWR (line wedge roughness), and etching durability, and can suppress degradation in smoothness of a film surface due to thermal expansion when the underlay film is heated.COPYRIGHT: (C)2015,JPO&INPIT

Efficient generation of dendritic arrays of cross-linked hemoglobin: Symmetry and redundancy

Chemically connected protein arrays have significant diverse applications including the production of red cell substitutes, bioconjugate drug delivery, and protein therapies. In order to make materials of defined structure, there is a need for efficient and accessible reagents. While chemical cross-linking with a multi-subunit protein can be achieved in high yield, connecting proteins to one another in a dendritic assembly along with concurrent cross-linking has met with limited success. This has now been overcome through the design and implementation of a readily prepared reagent with added reaction sites that compensate for competing hydrolysis. N,N′,N″-Tris[bis(sodium methyl phosphate)isophthalyl]-1,3,5-benzenetricarboxamide (1), a hexakis(methyl phosphate) isophthalyl trimesoyl tris-amide, was designed and synthesized in high yield in three stages from a reactive trimesoyl core. This material has three pairs of coplanar cross-linking reaction sites in a symmetrical array. The presence of three sets of sites greatly increases the probability that at least two sets will produce cross-links within hemoglobin tetramers (in competition with hydrolysis) and thereby connect two cross-linked tetramers at the same time. Reaction of 1 with deoxyhemoglobin at pH 8.5 gives a material that contains two cross-linked hemoglobin tetramers connected to one another and to a constituent αβ dimer. Products were characterized by SDS-PAGE, MS, enzyme digestion and HPLC. The isolated dendritic-hemoglobin with 2.5 tetrameric components has the same oxygen affinity as native hemoglobin (P50 = 5.0 torr) and retains cooperativity (n50 = 2.0). Analysis of circular dichroism spectra indicates that the assembly retains proper folding of the globin chains while the hemes are in an altered environment. The Royal Society of Chemistry 2008.

Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts

Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts useful as complement inhibitors.