40431-34-3Relevant academic research and scientific papers
A simple and efficient synthesis of methyl 3,4-dihydro-2-methyl-2H-1,2- benzothiazine-3-carboxylate 1,1-dioxide from saccharin sodium salt
Vidal, Aurelien,Madelmont, Jean-Claude,Mounetou, Emmanuelle
, p. 591 - 593 (2006)
A straightforward synthesis of methyl 3,4-dihydro-2-methyl-2H-1,2- benzothiazine-3-carboxylate 1,1-dioxide from saccharin sodium salt was achieved in five steps. Methyl 3,4-dihydro-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide found application as a precursor for the synthesis of a new class of quaternary ammonium derivatives that are potential antiosteoarthritis agents. Georg Thieme Verlag Stuttgart.
