404345-07-9Relevant academic research and scientific papers
Enantioselective route to key intermediates in the synthesis of carbocyclic phosphoribosyltransferase transition state analogues
Ahmadian, Mohammad,Khare, Naveen K.,Riordan, James M.,Klon, Anthony E.,Borhani, David W.
, p. 9899 - 9909 (2007/10/03)
The enantioselective preparation of key intermediates in the synthesis of transition state analogues of hypoxanthine-guanine phosphoribosyltransferase, (1S,2S,3R,4R)-4-acetoxymethyl-1-bromomethyl-2,3-isopropylidenedioxy-1- toluenesulfonamidocyclopentane (3a) and the 4-nitrobenzenesulfonamido analogue (3b), are described.
