404385-37-1

Basic information

• Product Name: Carbamic acid, [(2Z)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester
• Synonyms: Carbamic acid, [(2Z)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester
• CAS NO: 404385-37-1
• Molecular Formula: C9H16FNO3
• Molecular Weight: 205.2266432
• Product Categories: N-BOC
• Mol File: 404385-37-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 318.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.104±0.06 g/cm3(Predicted)
• PKA: 11.04±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, [(2Z)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(2Z)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester(404385-37-1)
• EPA Substance Registry System: Carbamic acid, [(2Z)-3-fluoro-4-hydroxy-2-butenyl]-, 1,1-dimethylethyl ester(404385-37-1)

Safety Data

• Hazardous Substances Data: 404385-37-1(Hazardous Substances Data)

Upstream product

• 137618-48-5 tert-butyl N-(2,3-dihydroxypropyl)carbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1158976-82-9 ethyl (E)-4-((tert-butoxycarbonyl)amino)-2-fluorobut-2-enoate 
• 89711-08-0 N-(t-butoxycarbonyl)glycinal 
• 404385-36-0 (E/Z)-ethyl 4-(tert-butoxycarbonylamino)-2-fluorobut-2-enoate 

Relevant articles and documents

DIFLUOROHALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES, METHODS OF PREPARATION, AND USES THEREOF

The present invention relates to methods for preparing a variety of difluorohaloallylamine derivatives. The present invention also relates to novel difluorohaloallylamine derivatives that are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for the treatment of a variety of indications, e.g., fibrosis, cancer and/or scarring in human subjects as well as in pets and livestock. In addition, the present invention relates to pharmaceutical compositions containing these compounds, as well as uses thereof.

Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3

Lysyl oxidase-like 2 (LOXL2) is a secreted enzyme that catalyzes the formation of cross-links in extracellular matrix proteins, namely, collagen and elastin, and is indicated in fibrotic diseases. Herein, we report the identification and subsequent optimi

INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF

The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i