40448-79-1

Upstream product

• 25131-60-6 2-phenacylisoquinolinium bromide 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 97204-12-1 (1R,2R,3R,10bR)-3-Benzoyl-1,2,3,10b-tetrahydro-pyrrolo[2,1-a]isoquinoline-1,2-dicarboxylic acid di-tert-butyl ester 
• 97204-10-9 8-benzoyl-10-methyl-11a,11b-dihydro-8H-pyrrolo[3',4':3,4]pyrrolo[2,1-a]isoquinoline-9,11(8aH,10H)-dione 
• 90069-65-1 methyl-3-benzoyl-2-hydroxy-1-pyrrolo<2,1-a>isoquinolinepentanoate 
• 90069-64-0 3-benzoyl-2-hydroxy-1-methylpyrrolo<2,1-a>isoquinoline 
• 97204-11-0 (1R,2R,3R,10bR)-3-Benzoyl-1,2,3,10b-tetrahydro-pyrrolo[2,1-a]isoquinoline-1,2-dicarboxylic acid dimethyl ester 
• 97204-09-6 ((1R,2R,3R,10bR)-2,3-Dibenzoyl-1,2,3,10b-tetrahydro-pyrrolo[2,1-a]isoquinolin-1-yl)-phenyl-methanone 
• 90069-62-8 3-benzoyl-2-(2-benzoylpropionyloxy)-1-methylpyrrolo<2,1-a>isoquinoline 
• 90069-63-9 7-benzoyl-5-oxo-1,2,3,4-tetrahydro-5H-oxocino<3',2';3,4>pyrrolo<2,1-a>isoquinoline 
• 90069-61-7 2-acetoxy-3-benzoyl-1-methylpyrrolo<2,1-a>isoquinoline 
• 90069-60-6 1,3-dibenzoyl-2-hydroxypyrrolo<2,1-a>isoquinoline 
• 84802-57-3 4-Methyl-N-[3,4,6-triphenyl-pyran-(2Z)-ylidene]-benzenesulfonamide 

Relevant academic research and scientific papers

Electrophilicities of 1,2-disubstituted ethylenes

The kinetics of the reactions of maleic anhydride, N-methylmaleimide, fumaronitrile, diethyl fumarate, and diethyl maleate with pyridinium and sulfonium ylides were studied in DMSO at 20 C. All of the reactions were found to follow a second-order rate law

REGIO- AND STEREODIRECTIVITY IN THE REACTIONS OF ISOQUINOLINIUM YLIDES WITH UNSATURATED NITRILES

Reactions of isoquinolinium ylides with arylmethylenemalonitriles involve 1,3-dipolar cycloaddition, with the highly regio- and stereoselective formation of 2-aryl-3-benzoyl(or carbamoyl)-1,1-dicyano-2,3-trans-1,2,3,10b-tetrahydropyrroloisoquinolines.In contrast, N-phenacylisoquinolinium ylide reacts with arylmethylenecyanothioacetamides differently, proceeding regio- and stereoselectively to give 4-aryl-2-hydroxy-3-(1-isoquinolinio)-2-phenyl-3-cyano-3,4-trans-1,2,3,4-tetrahydropyridine-6-thiolates.