404577-47-5Relevant academic research and scientific papers
Antiaggregatory activity in human platelets of potent antagonists of the P2Y1 receptor
Cattaneo, Marco,Lecchi, Anna,Ohno, Michihiro,Joshi, Bhalchandra V.,Besada, Pedro,Tchilibon, Susanna,Lombardi, Rossana,Bischofberger, Norbert,Harden, T. Kendall,Jacobson, Kenneth A.
, p. 1995 - 2002 (2004)
Activation of the P2Y1 nucleotide receptor in platelets by ADP causes changes in shape and aggregation, mediated by activation of phospholipase C (PLC). Recently, MRS2500 (2-iodo-N6-methyl-(N)-methanocarba- 2′-deoxyadenosine-3′,5′-bi
