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4,5-Dimethylpsoralen is a naturally occurring chemical compound belonging to the psoralen family, which is found in plants such as the Ammi majus and Psoralea corylifolia. It is a photosensitizing agent that, when combined with ultraviolet A (UVA) light, can be used in the treatment of various skin conditions like psoriasis, vitiligo, and eczema. The compound works by intercalating into DNA, causing cross-linking between strands and inhibiting DNA replication, which leads to the suppression of the rapid cell division associated with these skin disorders. Due to its photosensitizing properties, it is crucial to protect the skin from sunlight exposure during and after treatment with 4,5-Dimethylpsoralen.

4046-74-6

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4046-74-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4046-74-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,4 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4046-74:
(6*4)+(5*0)+(4*4)+(3*6)+(2*7)+(1*4)=76
76 % 10 = 6
So 4046-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H10O3/c1-7-3-13(14)16-12-6-11-9(5-10(7)12)4-8(2)15-11/h3-6H,1-2H3

4046-74-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-dimethylfuro[3,2-g]chromen-7-one

1.2 Other means of identification

Product number -
Other names 4-5'-dimethylpsoralen

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4046-74-6 SDS

4046-74-6Downstream Products

4046-74-6Relevant academic research and scientific papers

Treatment methods for lymes disease and associated debilitating conditions

-

, (2008/06/13)

A method is provided for treating human patients who have Lymes disease by using a psoralen compound, preferably administered in a dosage of 0.3 to 0.7 mg/kg, and activating same either in vitro or in vivo using electromagnetic radiation of a prescribed activating wavelength. The activation of the psoralen compound in the presence of a blood fraction from a patient suffering from Lymes disease produces a composition which will stimulate an effective immune response to the Lymes disease on the part of the patient.

Synthesis of linear and angular furocoumarins using intramolecular Wittig reaction: Part 31

Soman, Shubhangi S.,Trivedi, K. N.

, p. 532 - 534 (2007/10/02)

Synthesis of linear and angular furocoumarins has been achieved from 7-acetoxy-6-bromomethyl-4-methylbenzopyran-2(H)-one (2a) using intramolecular Wittig reaction.Linear and angular furocoumarins having phenyl substituent at 2-position have been synthesis

Treatment methods and vaccines for stimulating an immunological response against retroviruses

-

, (2008/06/13)

Human Immunodeficiency Virus infections, particularly AIDS, are treated by administering a psoralen compound which is subsequently activated by exposure to electromagnetic radiation (e.g. UVA light) whereby the activated psoralen compound attacks free virus and/or virus infected cells in the blood of the patient. The treated blood when presented to the patient's immune system engenders an effective immune response against the infection. The method has particular utility in the treatment of ARC patients who have depressed immune function.

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