40467-18-3

Basic information

• Product Name: 3,4-Dihydro-1-methyl-1H-2,1,3-benzothiadiazine 2,2-dioxide
• Synonyms: 3,4-Dihydro-1-methyl-1H-2,1,3-benzothiadiazine 2,2-dioxide
• CAS NO: 40467-18-3
• Molecular Formula: C8H10N2O2S
• Molecular Weight: 198.24
• Mol File: 40467-18-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Dihydro-1-methyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-1-methyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(40467-18-3)
• EPA Substance Registry System: 3,4-Dihydro-1-methyl-1H-2,1,3-benzothiadiazine 2,2-dioxide(40467-18-3)

Safety Data

• Hazardous Substances Data: 40467-18-3(Hazardous Substances Data)

Upstream product

• 33853-77-9 3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide 
• 74-88-4 methyl iodide 

Relevant articles and documents

Basicity of Nitrogen-Sulphur(VI) Compounds. Part 6. Ionization of NN'-Di- and N-Mono-substituted Sulphamides and Dihydro-2,1,3-benzothiadiazoline and Benzothiadiazine 2,2-Dioxides (Cyclic Sulphamides)

36 Di- and mono- and two tri-substituted sulphamides have been synthesised and their ionization equilibria in base (Schemes 1-3) have been studied.Many of the sulphamides are new materials.The pKa values obtained for each series have been correlated in Hammett and Taft plots.The Hammett ? values obtained for the ionization of the proximate hydrogen are ca. 2.3.The Taft ?* value obtained for ionization of the 'remoter' hydrogen is 1.68.The six-membered cyclic sulphamides are more acidic than their acyclic analogues by ca. 2.5 pKa units and the five-membered cyclic sulphamides are ca. 4 pKa units more acidic than model open-chain counterparts.Sulphur d-orbital involvement and ring-strain are suggested as possible sources of this 'acid-strengthening' effect.