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1-{[bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

40478-24-8

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Basic information
1. Product Name: 1-{[bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione
2. Synonyms: 1-{[Bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione; 2,5-pyrrolidinedione, 1-[[bis(2-chloroethyl)amino]methyl]-
3. CAS NO:40478-24-8
4. Molecular Formula: C₉H₁₄Cl₂N₂O₂
5. Molecular Weight: 253.1257
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 40478-24-8.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 342.4°C at 760 mmHg
3. Flash Point: 160.9°C
4. Appearance: N/A
5. Density: 1.333g/cm³
6. Vapor Pressure: 7.54E-05mmHg at 25°C
7. Refractive Index: 1.532
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: 1-{[bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione(CAS DataBase Reference)
11. NIST Chemistry Reference: 1-{[bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione(40478-24-8)
12. EPA Substance Registry System: 1-{[bis(2-chloroethyl)amino]methyl}pyrrolidine-2,5-dione(40478-24-8)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 40478-24-8(Hazardous Substances Data)

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40478-24-8 Usage

Functional groups

Two 2-chloroethyl groups
An amino group
A pyrrolidine-2,5-dione ring

Use

Alkylating agent in chemotherapy

Cancer treatment

Brain tumors
Lymphomas

Mechanism of action

Interferes with DNA replication and transcription, inhibiting tumor growth

Administration

Intravenous

Combination therapy

Effective when combined with other chemotherapy drugs

Toxicity

Highly toxic compound

Side effects

Bone marrow suppression
Damage to lungs and kidneys

Check Digit Verification of cas no

The CAS Registry Mumber 40478-24-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,4,7 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40478-24:
(7*4)+(6*0)+(5*4)+(4*7)+(3*8)+(2*2)+(1*4)=108
108 % 10 = 8
So 40478-24-8 is a valid CAS Registry Number.

40478-24-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-[bis(2-chloroethyl)aminomethyl]pyrrolidine-2,5-dione

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40478-24-8 SDS

40478-24-8Upstream product

40478-24-8Downstream Products

40478-24-8Relevant academic research and scientific papers

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