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2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-1-phenyl- is a chemical compound with the molecular formula C14H15NO. It belongs to the class of organic compounds known as benzazepines, which are a type of heterocyclic compound containing a benzene ring fused to a seven-membered azepine ring. This specific compound features a phenyl group attached to the nitrogen atom of the azepine ring, and it is a derivative of the parent compound 2H-3-benzazepin-2-one. It is an important intermediate in the synthesis of various pharmaceuticals and has potential applications in the development of drugs targeting the central nervous system. The compound is characterized by its unique structure and properties, which can be further explored for its potential therapeutic uses.

4048-78-6

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4048-78-6 Usage

Chemical structure

tricyclic compound with a benzazepine backbone and a ketone functional group

Potential pharmaceutical applications

being studied for use as an antidepressant and antipsychotic agent

Mechanism of action

acts on the central nervous system and has binding affinity for serotonin and dopamine receptors

Investigated for

potential in treating addiction and substance abuse disorders

Ongoing research

exploring the full range of potential therapeutic uses

Check Digit Verification of cas no

The CAS Registry Mumber 4048-78-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,4 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4048-78:
(6*4)+(5*0)+(4*4)+(3*8)+(2*7)+(1*8)=86
86 % 10 = 6
So 4048-78-6 is a valid CAS Registry Number.

4048-78-6Relevant academic research and scientific papers

Palladium Complexes Bearing Mesoionic Carbene Ligands: Applications in α-Arylation, α-Methylation and Suzuki-Miyaura Coupling Reactions

Maity, Ramananda,Verma, Amit,Van Der Meer, Margarethe,Hohloch, Stephan,Sarkar, Biprajit

, p. 111 - 117 (2016)

Complexes of mesoionic carbene (MIC) ligands are gaining immense popularity in organometallic chemistry and homogeneous catalysis. We present here a series of palladium(II) complexes that are comprised of MIC donor ligands, and we demonstrate their applic

Synthesis of Novel Heterocycles by Amide Activation and Umpolung Cyclization

Maulide, Nuno,Riomet, Margaux,Roller, Alexander,Zhang, Haoqi

, (2020/03/24)

Herein, we report a metal-free synthesis of cyclic amidines, oxazines, and an oxazinone under mild conditions by electrophilic amide activation. This strategy features an unusual Umpolung cyclization mode and enables the smooth union of α-aryl amides and diverse alkylazides, effectively rerouting our previously reported α-amination transform.

Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents

-

, (2008/06/13)

Novel imidazo[2,1-b][3]benzazepines and pyrimido[2,1-b][3]benzazepines of formula I, pharmaceutical compositions containing them, methods for treating cardiac arrhythmia in mammals utilizing them, and processes for synthesizing them. STR1

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