404859-27-4

Basic information

• Product Name: 5-Oxazolidinone, 3-benzoyl-4-[(2E)-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-butenyl]- 2-(1,1-dimethylethyl)-4-methyl-, (2S,4R)-
• CAS NO: 404859-27-4
• Molecular Formula: C27H28N2O5
• Molecular Weight: 460.53
• Mol File: 404859-27-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Oxazolidinone, 3-benzoyl-4-[(2E)-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-butenyl]- 2-(1,1-dimethylethyl)-4-methyl-, (2S,4R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxazolidinone, 3-benzoyl-4-[(2E)-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-butenyl]- 2-(1,1-dimethylethyl)-4-methyl-, (2S,4R)-(404859-27-4)
• EPA Substance Registry System: 5-Oxazolidinone, 3-benzoyl-4-[(2E)-4-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-butenyl]- 2-(1,1-dimethylethyl)-4-methyl-, (2S,4R)-(404859-27-4)

Safety Data

• Hazardous Substances Data: 404859-27-4(Hazardous Substances Data)

Upstream product

• 404859-23-0 (E)-2-(4-iodobut-2-en-1-yl)isoindoline-1,3-dione 
• 104057-64-9 (2S,4S)-3-benzoyl-2-(tert-butyl)-4-methyl-1,3-oxazolidin-5-one 

Relevant articles and documents

COMBINATION THERAPY WITH INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND ALKYLATING AGENTS

A combination therapy comprising administration of a carbamoylating chemotherapeutic agent in conjunction with administration of a selective iNOS inhibitor compound is disclosed. Optionally, resection and radiation therapy are provided with the therapeutic combination. A medicament comprising a carbamoylating chemotherapeutic agent and a selective iNOS inhibitor compound together with a pharmaceutically acceptable carrier is further disclosed. A kit comprising a carbamoylating chemotherapeutic agent and a selective iNOS inhibitor compound is further disclosed.