40503-14-8

Upstream product

• 13482-22-9 4-hydroxycyclohexanone 
• 28987-79-3 m-tolylmagnesium bromide 

Downstream Products

• 40503-23-9 4-m-Tolylcyclohex-3-en-1-ol 
• 40503-34-2 Methanesulfonic acid 4-m-tolyl-cyclohex-3-enyl ester 
• 40503-89-7 4-(3-methylphenyl)cyclohexan-1-one 

Relevant academic research and scientific papers

4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2

The present invention comprises compounds of Formula (I): wherein: X, R1, R2, R3, and R4 are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).

4'-Fluoro-4-{[4-(phenyl)-4-alkoxy-cyclo-hexyl]amino}butyrophenones and the salts thereof

This invention relates to novel 4-(substituted alkoxy)-4-(substituted phenyl)cyclohexylamines embraced by the formula SPC1 Wherein ? is a generic expression denoting cis and trans stereoconfiguration and mixtures thereof, with the proviso that when the st