405071-50-3

Upstream product

• 76263-11-1 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylate 
• 30132-23-1 ethyl 3-bromo-2-oxocyclohexanecarboxylate 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Downstream Products

• 405071-51-4 toluene-4-sulfonic acid 2-amino-4,5,6,7-tetrahydro-benzothiazol-4-ylmethyl ester 

Relevant academic research and scientific papers

MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are multicyclic compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

A convenient synthesis of 4-aminomethyl-4,5,6,7-tetrahydro-1,3-benzothiazole arginine side-chain mimetics

A convenient synthesis of novel 4-aminomethyl-4,5,6,7-tetrahydro-1,3-benzothiazole arginine side-chain mimetics designed for incorporation into thrombin inhibitors is reported.