405137-17-9Relevant articles and documents
New syntheses of orelline and analogues via metalation and cross-coupling reactions
Mongin, Florence,Trécourt, Fran?ois,Mongin, Olivier,Quéguiner, Guy
, p. 309 - 314 (2002)
New total syntheses of orelline and some analogues are reported. The methodology involves metalation of 3-alkoxy-2-iodopyridines to afford 3,4-dialkoxy-2-iodopyridines, on which cross-coupling reactions are performed to reach the 2,2′-bipyridine skeleton of the alkaloid.