40514-66-7Relevant academic research and scientific papers
ORGANIC REACTIONS AT HIGH PRESSURE. WITTIG REACTION OF HINDERED KETONES WITH NONSTABILIZED YLIDES.
Dauben, William G.,Takasugi, James J.
, p. 4377 - 4380 (2007/10/02)
The Wittig reaction between n-butylidenetriphenylphosphorane and a series of cyxclohexanones of increasing steric hindrance around the carbonyl group has been studied at 7 kbar and 15 kbar pressure (0.75-1.5 GPa) and at 40 deg C.In all cases, except 2,2,6
THE WITTIG REACTION USING POTASSIUM-TERT-BUTOXIDE HIGH YIELD METHYLENATIONS OF STERICALLY HINDERED KETONES
Fitjer, Lutz,Quabeck, Ulrike
, p. 855 - 864 (2007/10/02)
Potassium-tert-butoxide is recommended for general use in Wittig reactions with nonstabilized ylides.High yield methylenations of cyclohexanone and a series of five sterically hindered ketones demonstrate its utility.
