40520-87-4

Usage

Chemical classification

Stable nitroxide radical

Antioxidant properties

Potent antioxidant and free radical scavenger

Neuroprotective effects

Protects neurons from damage caused by oxidative stress

Anti-inflammatory effects

Reduces inflammation in the body

Anti-tumor properties

Inhibits the growth of cancer cells

Applications in treating diseases

Cardiovascular diseases, diabetes, and other conditions related to oxidative stress

Preservation of organs for transplantation

Prolongs the life of organs outside the body

Prevention of tissue damage

Reduces damage during ischemia reperfusion injury

Promising candidate

For various medical and industrial applications due to its beneficial properties

Upstream product

• 132898-61-4 2,2,6,6-tetramethylpiperidin-4-yl 4-hydroxybenzoate 
• 99-96-7 4-hydroxy-benzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 2403-88-5 4-hydroxy-2,2,6,6-tetramethylpiperidine 

Relevant academic research and scientific papers

Reactions of nitroxides. Part VIII [1]: Nitroxides with a cyanato substituent

Nitroxides bearing a cyanato group were synthesized from nitroxides containing a phenolic hydroxyl group using both cyanogen chloride and bromide.

AMELIORATION OF CATARACTS, MACULAR DEGENERATION AND OTHER OPHTHALMIC DISEASES

Ophthalmically acceptable compositions used in arresting the development of cataract, presbyopia, macular degeneration and other retinopathies, glaucoma, uveitis and various corneal disorders are disclosed. The compositions are also useful as a prophylactic treatment to prevent or delay development of age-related ocular disorders, which include cataracts, presbyopia, glaucoma and macular degeneration. The compositions comprise a pharmaceutically acceptable carrier or diluent and at least one compound having the formula where R1 and R2 are, independently, H or C1 to C3 alkyl ; R3 and R4 are, independently C1 to C3 alkyl; and where R1 and R2, taken together, or R3 and R4, taken together, or both may be cycloalkyl; R5 is H, OH, or C1 to C6 alkyl ; R6 is or C1 to C6 alkyl, alkenyl, alkynyl, or substituted alkyl or alkenyl ; R7 is C1 to C6 alkyl, alkenyl, alkynyl, or substituted alkyl or alkenyl or where R6 and R7, or R5, R6 and R7, taken together, form a carbocycle or heterocycle having from 3 to 7 atoms in the ring.

Synthesis of Novel Hydroxy-Substituted Aromatic Aminoxyl Esters and their Azo Derivatives

Transesterification or acylation methods has been used for the preparation of three novel hydroxy-substituted aromatic aminoxyl esters 4, 5, and 8 from which three new spin-labelled azo compounds 10, 13, and 14 have been synthesized. Key words: Synthesis;