405211-89-4Relevant academic research and scientific papers
Synthesis and resolution of β2,2-HBin, the first enantiomerically stable β-amino acid with chirality only due to axial dissymmetry
Gaucher, Anne,Zuliani, Yohan,Cabaret, Daniel,Wakselman, Michel,Mazaleyrat, Jean-Paul
, p. 2571 - 2580 (2007/10/03)
The first gem-disubstituted β2,2-amino acid possessing only axial chirality, was synthesized by bis-alkylation of methyl or ethyl cyanoacetate with both racemic and enantiomerically pure (R)-2,2′-bis-(bromomethyl)-1,1′-binaphthyl, followed by N
