40523-67-9

Upstream product

• 124021-39-2 (+/-)-trans-2-acetoxy-1-methyl-cyclohexene-⁽³⁾ 
• 75337-05-2 4-methyl-2-cyclohexenone 
• 591-47-9 4-methylcyclohexene 
• 62392-84-1 (+)-(R)-6-methylcyclohex-2-en-1-one 

Downstream Products

• 6610-21-5 6-methylcyclohex-2-en-1-one 
• 78168-31-7 (2RS)-N,N-Diethyl-2<(1SR,4SR)-4-Methyl-2-cyclohexenyl>propanamide 
• 78215-31-3 (2RR)-N,N-Diethyl-2<(1SS,4SS)-4-Methyl-2-cyclohexenyl>propanamide 
• 7443-52-9 (+/-)-trans-2-methylcyclohexanol 

Relevant academic research and scientific papers

Regioselectivity in the palladium-catalyzed addition of carbon nucleophiles to carbocyclic derivatives

The regioselectivity of Pd-catalyzed malonate additions and arylations to cycloalkenyl esters can be predicted by completing a stereochemical analysis of the Pd-π-allyl complex. The Pd-catalyzed malonate additions which have the greatest degree of regioselectivity are in which substituents have a steric influence in blocking the incoming nucleophile. Cyclopentenyl substrates displayed lower regioselectivity than the cyclohexyl counterparts presumably due to increased planarity of the system. Arylations using tin and hypervalent silicon reagents were compared.

Total Synthesis of Dihydrovitamin DHV3 and Dihydrotachysterol DHT3. Application of the Low-Valent Titanium-Induced Reductive Elimination

Optically active ring A synthons 6, 11, 13, and 14, precursors of DHV3 and DHT3, were synthetized from (-)- and (+)-carvone.Application of the low-valent titanium-induced reductive elimination gave a new synthetic approach to vitamin D3 analogues, as show