405238-83-7 Usage
General Description
[(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol is a chemical compound that consists of a furan ring with a hydroxymethyl group attached to it, as well as a purine ring with two amino groups. It has a specific stereochemistry, with the 2S and 5R configurations. [(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol is a derivative of the nucleoside adenosine and has potential applications in pharmaceutical research, particularly in the development of antiviral drugs and nucleoside analogues. Its specific structure and functional groups make it a valuable compound for studying the interactions and mechanisms of action of nucleosides and related compounds in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 405238-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,5,2,3 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 405238-83:
(8*4)+(7*0)+(6*5)+(5*2)+(4*3)+(3*8)+(2*8)+(1*3)=127
127 % 10 = 7
So 405238-83-7 is a valid CAS Registry Number.
405238-83-7Relevant articles and documents
Structure-activity relationships of 2′-fluoro-2′,3′-unsaturated d-nucleosides as anti-hiv-1 agents
Lee, Kyeong,Choi, Yongseok,Gumina, Giuseppe,Zhou, Wen,Schinazi, Raymond F.,Chu, Chung K.
, p. 1313 - 1320 (2002)
We studied the structure-activity relationships of a series of 2′-fluoro-2′,3′-unsaturated D-nucleosides against HIV-1 in human peripheral blood mononuclear (PBM) cells. The target compounds 10-21 and 28-33 were prepared by N-glycosylation of the acetate