405239-71-6

Usage

General Description

1-[2-(Cyclopropylmethoxy)-6-[(4-methoxyphenyl)methoxy]phenyl]ethanone is a chemical compound with a complex structure and is often used in the field of pharmaceutical research. It is a ketone compound with a cyclopropylmethoxy group and a 4-methoxyphenylmethoxy group attached to a central benzene ring. 1-[2-(Cyclopropylmethoxy)-6-[(4-methoxyphenyl)methoxy]phenyl]ethanone has potential use in the development of new medications due to its unique structure and potential pharmaceutical properties. It may have applications for the treatment of various medical conditions or as a building block in the synthesis of other compounds. Further research and testing are likely needed to fully understand its properties and potential applications.

Upstream product

• 311-28-4 tetra-(n-butyl)ammonium iodide 
• 824-94-2 p-methoxybenzyl chloride 
• 405239-70-5 1-{2-[(cyclopropylmethyl)oxy]-6-hydroxyphenyl}ethanone 
• 699-83-2 2,6-dihydroxylacetophenone 

Downstream Products

• 406213-57-8 2'-amino-3'-cyano-6'-[2-cyclopropylmethoxy-6-(4-methoxy-benzyloxy)-phenyl]-3,4,5,6-tetrahydro-2H-[4,4']bipyridinyl-1-carboxylic acid tert-butyl ester 
• 405239-75-0 tert-butyl 2-amino-4-[1-(tert-butoxycarbonyl)-3-piperidinyl]-6-{2-(cyclopropyl-methoxy)-6-[(4-methoxybenzyl)oxy]phenyl}nicotinate 
• 405239-70-5 1-{2-[(cyclopropylmethyl)oxy]-6-hydroxyphenyl}ethanone 
• 433960-75-9 tert-butyl 2-amino-6-{2-(cyclopropylmethoxy)-6-[(4-methoxybenzyl)oxy]phenyl}-4-(3-hydroxy-4-nitrophenyl)nicotinate 
• 406213-49-8 1-{2-(cyclopropylmethoxy)-6-[(4-methoxybenzyl)oxy]phenyl}-3,3-bis(methylsulfanyl)-2-propene-1-one 
• 406208-42-2 2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-piperidin-4-yl nicotinonitrile 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of novel IKK-β inhibitors. Part 3: Orally active anti-inflammatory agents

A series of 2-amino-3-cyano-4-alkyl-6-(2-hydroxyphenyl)pyridine derivatives was synthesized and evaluated as IκB kinase β (IKK-β) inhibitors. Modification of a novel IKK-β inhibitor 1 (IKK-β IC 50=1500nM, Cell IC50=8000nM) at the 4-p

Pyridine derivatives

Pyridine compounds of general formula: wherein —R1represents in which R11is hydrogen, C1-6alkyl, halogen, hydroxy, C1-12alkoxy, nitro, amino, C1-6alkylsulfonylamino, C1-6alkoxycarbonyl, C1-6alkylamino, di(C1-6alkyl)amino, C1-6alkanoylamino, phenyl C1-6alkylamino, phenylsulfonylamino, or —O—(CH2)n—R111; R2represents hydrogen or halogen; R3represents hydrogen, —CR31R32R33, or —NR34R35; R4is hydrogen, carbamoyl, CN, carboxyl, etc.; R5is amino, C1-6alkylamino, di C1-6alkylamino, etc. or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological activity.

AN OPTICALLY ACITVE PYRIDINE DERIVATIVE AND A MEDICAMENT CONTAINING THE SAME

An optically active (-)-7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-[(3S)-3-piperidinyl]-1,4-dihydro-2H-pyrido [2,3-d][1,3]oxazin-2-one of the formula (I) or salt thereof. The compound has an excellent anti-inflammatory activity, and other biological act