405275-23-2Relevant academic research and scientific papers
Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]- 1H-indoles: Potent and selective aromatase inhibitors
Leze, Marie-Pierre,Le Borgne, Marc,Pinson, Patricia,Palusczak, Anja,Duflos, Muriel,Le Baut, Guillaume,Hartmann, Rolf W.
, p. 1134 - 1137 (2007/10/03)
The synthesis and the aromatase (CYP19) inhibitory activity of 5-[(aryl)(imidazol-1-yl)methyl]-1H-indoles were reported. Among the tested racemate compounds, 5-[(4-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-indole 8b emerged as a potent CYP19 inhibitor (IC
Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition
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Page/Page column 18-19, (2010/02/06)
The present invention relates to novel indole derivatives, their method of preparation and their pharmacological activity as antimycotic and/or antiparasitic compounds.
