405277-41-0

Upstream product

• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 555-16-8 4-nitrobenzaldehdye 
• 16837-06-2 p-(3,3,4,4-tetramethyl-2,5-dioxa-1-borolyl)nitrobenzene 

Downstream Products

• 1312201-85-6 (4-(((4-formylphenyl)amino)methyl)phenyl)boronic acid 
• 1312201-87-8 (Z)-(4-(((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)amino)methyl)phenyl)boronic acid 
• 1255148-35-6 3-{4-[4-(1-phenylethyl)amino]phenyl}-2-furan carboxylic acid-2-(4-hydroxy-3-nitrobenzoyl)hydrazide hydrochloride 
• 1255149-59-7 C₂₀H₁₈N₄O₇*ClH 
• 1255148-27-6 3-(4-{[1-(4-methylphenyl)ethyl]amino}phenyl)-2-furan carboxylic acid-2-(4-hydroxy-3-nitrobenzoyl)hydrazide hydrochloride 
• 1255149-56-4 3-(4-aminophenyl)-2-furan carboxylic acid 2-(4-hydroxy-3-nitrobenzoyl)hydrazide hydrochloride 
• 1255149-55-3 3-(4-aminophenyl)-2-furancarboxylic Acid hydrazide 
• 1255149-54-2 ethyl 3-(4-aminophenyl)-2-furan carboxylate 

Relevant academic research and scientific papers

Structure-based design of novel boronic acid-based inhibitors of autotaxin

Autotaxin (ATX) is a secreted phosphodiesterase that hydrolyzes the abundant phospholipid lysophosphatidylcholine (LPC) to produce lysophosphatidic acid (LPA). The ATX-LPA signaling axis has been implicated in inflammation, fibrosis, and tumor progression