405278-65-1Relevant academic research and scientific papers
Diversity-oriented synthesis of substituted pyrazolo-[4,3-d][1,2,3]triazin-4-ones
Meibom, Daniel,Bauser, Marcus,Meier, Heinrich,Schneider, Dirk,Svenstrup, Niels,Haebich, Dieter
experimental part, p. 71 - 91 (2009/05/07)
An efficient synthesis of 3,7-disubstituted 3,5-dihydro-4H-pyrazolo-[4,3-d][1,2,3]triazin-4-ones (2), especially suited for late-stage decoration, is described. Diverse 3-benzyl analogs were obtained by amidation-cyclization in one pot and various pyrazol
Pyrazole Compound
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Page/Page column 29, (2009/07/03)
The present invention provides a pyrazole compound represented by the formula (I): wherein ring A0 is a pyrazole ring optionally further having 1 or 2 substituents; Ra is a substituted carbamoyl group; and Rb is an optionally substituted acylamino group, or a salt thereof or a prodrug thereof, which is useful as an agent for the prophylaxis or treatment of GSK-3β related pathology or disease, and a GSK-3β inhibitor including same.
PYRAZOLE COMPOUND
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Page/Page column 41, (2010/11/28)
The present invention provides a pyrazole compound represented by the formula (I): wherein ring A0 is a pyrazole ring optionally further having 1 or 2 substituents; Ra is a substituted carbamoyl group; and Rb is an optionally substituted acylamino group, or a salt thereof or a prodrug thereof, which is useful as an agent for the prophylaxis or treatment of GSK-3β related pathology or disease, and a GSK-3β inhibitor including same.
