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7-Nitro-5-(trifluoromethyl)-2-Benzothiazolecarboxamide 3-oxide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

40533-25-3

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40533-25-3 Usage

Uses

Cyclapolin 9 is a selective and ATP-competitive Plk inhibitor.

Biological Activity

Selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC 50 = 500 nM).

Check Digit Verification of cas no

The CAS Registry Mumber 40533-25-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,5,3 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40533-25:
(7*4)+(6*0)+(5*5)+(4*3)+(3*3)+(2*2)+(1*5)=83
83 % 10 = 3
So 40533-25-3 is a valid CAS Registry Number.

40533-25-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Cyclapolin 9

1.2 Other means of identification

Product number -
Other names 5-methylpyridazinecarboxamide 4-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40533-25-3 SDS

40533-25-3Downstream Products

40533-25-3Relevant academic research and scientific papers

The Meisenheimer Complex as a Paradigm in Drug Discovery: Reversible Covalent Inhibition through C67 of the ATP Binding Site of PLK1

Pearson, Russell J.,Blake, David G.,Mezna, Mokdad,Fischer, Peter M.,Westwood, Nicholas J.,McInnes, Campbell

, p. 1107 - 4,1116 (2018)

The polo kinase family are important oncology targets that act in regulating entry into and progression through mitosis. Structure-guided discovery of a new class of inhibitors of Polo-like kinase 1 (PLK1) catalytic activity that interact with Cys67 of th

BENZTHIAZOLE-3 OXIDES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

-

Page/Page column 25-26, (2008/06/13)

The present invention relates to the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, and R4 are each independently H, N02, CF3, SCF

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