40538-50-9 Usage
General Description
1-methyl-1-(2-oxo-2-phenylethyl)piperidinium is a chemical compound that belongs to the class of piperidinium derivatives. It is a quaternary ammonium compound with a piperidine ring and a phenylethyl substitution at the nitrogen atom. 1-methyl-1-(2-oxo-2-phenylethyl)piperidinium is commonly used as a precursor in the synthesis of various pharmaceuticals and organic compounds. It is also employed as a catalyst in organic reactions and as a building block in the development of new materials. Additionally, it has been studied for its potential pharmacological properties, including its role as an inhibitor of enzymes and receptors in the nervous system. Overall, 1-methyl-1-(2-oxo-2-phenylethyl)piperidinium has a wide range of applications in the fields of chemistry, pharmaceuticals, and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 40538-50-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,5,3 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 40538-50:
(7*4)+(6*0)+(5*5)+(4*3)+(3*8)+(2*5)+(1*0)=99
99 % 10 = 9
So 40538-50-9 is a valid CAS Registry Number.
40538-50-9Relevant articles and documents
INTRAMOLECULAR CATALYSIS IN THE ENOLISATION OF AMINOKETONES
Cox, Brian G.,Maria Paolo De,Fini Adamo
, p. 1647 - 1652 (2007/10/02)
Measurements are reported on the rates of halogenation of the aminoketones PhCO(CH2)nNC5H10, with n = 1-3 , and N-methyl-4-piperidone (V), and their N-methyl derivatives.The reactions are zero order with respect to halogen concentration, with the rate-determining step being the formation of the enol or enolate ion.Large rate accelerations relative to acetophenone and cyclohexanone were observed, and these cannot be explained entirely in terms of inductive (through-bond) effects of =NH+, =NMe+, or =N groups.Other important factors are (i) intramolecular stabilization of the developing negative charge by the positive ammonium ion, the maximum effects being observed for (II); (ii) electrostatic interactions with negatively charged catalysts; (iii) direct proton transfer from the ionising C-H group to =N, acting as an intramolecular base catalyst.Evidence for a direct proton transfer was found only in reactions of the γ-substituted aminoketone (IV).
