405506-73-2Relevant articles and documents
A convenient route to alkaloid lipids: Application for the synthesis of a leptophylline A analogue
Koulocheri,Pitsinos,Haroutounian
, p. 111 - 115 (2007/10/03)
A synthetic route for efficient access to alkaloid lipids, using the chiral 2,3,6-trisubstituted piperidine acetaldehyde 9 as an intermediate, is reported. The utility of the synthetic route was demonstrated in the asymmetric synthesis of an unnatural analogue of Cassia leptophylla alkaloid lipid, leptophyllin A, in 16 steps and 15% overall yield starting from D-glucal.