40567-16-6

Basic information

• Product Name: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride
• Synonyms: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride;2-[2,4-bis(1,1-dimethylpropyl)phenoxy]-Butanoyl chloride 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]-butanoyl chlorid;2-(2,4-Di-tert-amylphenoxy)-butyryl chloride;2-(2,4-Di-tert-pentylphenoxy)butanoic acid chloride
• CAS NO: 40567-16-6
• Molecular Formula: C₂₀H₃₁ClO₂
• Molecular Weight: 338.91194
• EINECS: 254-978-0
• Mol File: 40567-16-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 392.1°Cat760mmHg
• Flash Point: 143.9°C
• Appearance: /
• Density: 1.002g/cm³
• Vapor Pressure: 2.35E-06mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride(40567-16-6)
• EPA Substance Registry System: 2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride(40567-16-6)

Safety Data

• Hazardous Substances Data: 40567-16-6(Hazardous Substances Data)

Usage

General Description

2-[2,4-bis(1,1-dimethylpropyl)phenoxy]butyryl chloride is a chemical compound with the molecular formula C18H29ClO2. It is a type of butyryl chloride, which is a derivative of butyric acid. This particular compound contains a butyryl functional group and a phenoxy group, both of which are substituted with 1,1-dimethylpropyl groups. It is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development of new chemical compounds. It is a colorless to pale yellow liquid with a strong, pungent odor, and it is highly reactive and corrosive, requiring careful handling and storage.

InChI:InChI=1/C20H31ClO2/c1-8-16(18(21)22)23-17-12-11-14(19(4,5)9-2)13-15(17)20(6,7)10-3/h11-13,16H,8-10H2,1-7H3

Upstream product

• 13403-01-5 2-(2,4-di-tert-pentylphenoxy)butyric acid 

Downstream Products

• 102580-11-0 4-[α-(2,4-ditert.-pentylphenoxy)-butyroyl]-6-benzyloxy-7-nitro-1,4-benzoxazine-3-one 
• 1219449-11-2 C₂₂H₃₄N₄O₂ 
• 38881-05-9 N-(4-Amino-2-hydroxy-phenyl)-2-[2,4-bis-(1,1-dimethyl-propyl)-phenoxy]-butyramide 
• 38881-04-8 2-[2,4-Bis-(1,1-dimethyl-propyl)-phenoxy]-N-(2-hydroxy-4-nitro-phenyl)-butyramide 
• 94109-73-6 {4-[2-(2,4-di-tert-pentyl-phenoxy)-butyrylamino]-phenoxy}-acetic acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 
• 31037-84-0 2-(2,4-di-tert-pentyl-phenoxy)-butyric acid-(3,5-dichloro-2-hydroxy-4-methyl-anilide) 

Relevant articles and documents

Process for producing aromatic amide compounds

There is disclosed a process for producing an aromatic amide compound of the general formula (4), including the steps of subjecting an o-nitrophenol compound of the general formula (1) to catalytic reduction in acetone or an aromatic hydrocarbon solvent under the presence of a nickel catalyst to give an o-aminophenol compound of the general formula (2); and (b) subjecting the o-aminophenol compound of the general formula (2) to condensation with an acid chloride compound having a sulfur content of 0.5% or less, based on the weight of the acid chloride compound, of the general formula (3) in acetone or an aromatic hydrocarbon solvent under an atmosphere of an inert gas having an oxygen concentration of 1% or less. The acid chloride compound having a sulfur content of 0.5% or less, based on the weight of the acid chloride compound, of the general formula (3) may be obtained by allowing a carboxylic acid compound of the general formula (5) to react with thionyl chloride and by concentrating the reaction mixture. Also disclosed is another process for producing an aromatic amide compound of the general formula (4), including the step of subjecting an o-aminophenol hydrochloride salt of the general formula (6) to condensation with an acid chloride compound having a sulfur content of 0.8% or less, based on the weight of the acid chloride compound, of the general formula (3) in an inert solvent.