405885-46-3

Upstream product

• 405885-43-0 (3aR,5S,7aS)-2,2-Dimethyl-hexahydro-benzo[1,3]dioxole-5-carbonitrile 
• 1380226-08-3 (5S,6R)-methyl 2-fluoro-5,6-dihydroxycyclohexa-1,3-dienecarboxylate 
• 1380226-13-0 (3aR,7aS)-methyl 5-fluoro-2,2-dimethyl-3a,7a-dihydrobenzo[d][1,3]dioxole-4-carboxylate 
• 1380226-16-3 (3aR,4R,7aS)-methyl 2,2-dimethylhexahydrobenzo[d][1,3]dioxole-4-carboxylate 
• 394-35-4 methyl 2-fluorobenzoate 
• 151622-68-3 methyl (+)-cis-(1S,2R)-1,2-dihydroxycyclohexa-3,5-diene-3-carboxylate 
• 128946-52-1 (1S,3R,4R,5R)-3,4-O-isopropylidene-3,4,5-trihydroxy-1-carboxy cyclohexane 1,5-lactone 
• 32384-42-2 (1S,3R,4S,5R)-3,4-O-isopropylidene-1,5-quinic lactone 
• 77-95-2 D-(-)-quinic acid 
• 58886-27-4 Acetic acid (S)-1-((R)-1,2-diacetoxy-ethyl)-4-oxo-butyl ester 
• 2873-29-2 D-glucal triacetate 
• 405885-35-0 Toluene-4-sulfonic acid (2R,3S)-6-cyano-2,3-dihydroxy-hexyl ester 
• 405885-25-8 Acetic acid (S)-1-((R)-1,2-diacetoxy-ethyl)-4-hydroxy-butyl ester 
• 405885-30-5 Acetic acid (S)-4-cyano-1-((R)-1,2-diacetoxy-ethyl)-butyl ester 

Relevant academic research and scientific papers

Facile synthesis of the cyclohexane fragment of enacloxins, a series of antibiotics isolated from Frateuria sp. W-315

An efficient and good yield synthesis of the cyclohexane moiety of enacyloxins, a series of antibiotics isolated from Frateuria sp. W-315, was achieved from D-quinic acid using a successive Barton - McCombie deoxygenation.

Toluene dioxygenase mediated oxidation of halogen-substituted benzoate esters

A series of ortho-, meta-, and para- halogen-substituted methyl benzoate esters was subjected to enzymatic dihydroxylation via the whole-cell fermentation with E. coli JM109 (pDTG601A). Only ortho-substituted benzoates were metabolized. Methyl 2-fluorobenzoate yielded one diol regioselectively whereas methyl 2-chloro-, methyl 2-bromo- and methyl 2-iodobenzoates each yielded a mixture of regioisomers. Absolute stereochemistry was determined for all new metabolites. Computational analysis of these results and a possible rationale for the regioselectivity of the enzymatic dihydroxylation is advanced.

Stereochemistry of enacyloxins 1. Absolute configuration of the cyclohexane ring part of enacyloxins, a series of antibiotics from Frateuria sp. W-315

The stereochemical study of the cyclohexane ring part of enacyloxins (ENXs), a series of antibiotics isolated from Frateuria sp. W-315, was examined. The relative configuration was elucidated by the coupling constant values of the 1H NMR spectr