405907-68-8Relevant academic research and scientific papers
N-arylpiperazine-1-carboxamide derivatives: A novel series of orally active nonsteroidal androgen receptor antagonists
Kinoyama, Isao,Taniguchi, Nobuaki,Kawaminami, Eiji,Nozawa, Eisuke,Koutoku, Hiroshi,Furutani, Takashi,Kudoh, Masafumi,Okada, Minoru
, p. 402 - 409 (2007/10/03)
A novel series of N-arylpiperazine-1-carboxamide derivatives was synthesized and their androgen receptor (AR) antagonist activities and in vivo antiandrogenic properties were evaluated. Reporter assays indicated that trans-2,5-dimethylpiperazine derivativ
