405915-54-0Relevant academic research and scientific papers
Transfer of Chirality in the Rhodium-Catalyzed Intramolecular Formal Hetero-[5 + 2] Cycloaddition of Vinyl Aziridines and Alkynes: Stereoselective Synthesis of Fused Azepine Derivatives
Feng, Jian-Jun,Lin, Tao-Yan,Wu, Hai-Hong,Zhang, Junliang
, p. 3787 - 3790 (2015)
By taking advantage of vinyl aziridines as a heteroatom-containing five-atom component in rhodium-catalyzed intramolecular formal hetero-[5 + 2] cycloaddition reactions with alkynes, a highly efficient method for the synthesis of fused azepine derivatives
Highly stereoselective samarium(II) iodide-mediated aldol reactions of acylaziridines with aldehydes
Ogawa, Yasuyuki,Kuroda, Kiichi,Mukaiyama, Teruaki
, p. 1309 - 1333 (2007/10/03)
The samarium(II) iodide-mediated stereoselective aldol reactions of acylaziridines with aldehydes are described. β-Amino-β′-hydroxy ketones were synthesized in high yields by the aldol reaction of aldehydes with samarium enolates generated by aziridine-fr
A Suzuki cross-coupling route to substituted aziridines
Lapinsky, David J,Bergmeier, Stephen C
, p. 8583 - 8586 (2007/10/03)
We have shown that the Suzuki cross-coupling reaction of olefinic aziridines is an effective route for the synthesis of substituted aziridines. This is the first example of a palladium coupling reaction applied to an aziridine-containing molecule. This method is complementary to other methods of aziridine synthesis utilizing organocuprate reagents.
