40594-83-0

Usage

Derivative of pyridine

The compound is derived from pyridine, a heterocyclic compound with a six-membered ring consisting of five carbon atoms and one nitrogen atom.

Ethane-1,2-diol moiety

The compound contains a two-carbon chain with two hydroxyl (-OH) groups attached to the first and second carbon atoms.

Unique structure

The combination of the pyridine ring and the ethane-1,2-diol moiety gives the compound a unique structure.

Potential applications

1-pyridin-3-yl-ethane-1,2-diol has potential uses in various fields, such as pharmaceuticals, organic synthesis, and biochemical research.

Variable properties and uses

The specific properties and potential applications of the compound may differ depending on the context and intended application.

Upstream product

• 1121-55-7 3-vinylpyridine 
• 60699-67-4 3-[(RS)-2-oxiranyl]pyridine 

Relevant academic research and scientific papers

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I, II, III, IV, V, and VI) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.

Microbiological transformations. 47. A step toward a green chemistry preparation of enantiopure (S)-2-, -3-, and -4-pyridyloxirane via an epoxide hydrolase catalyzed kinetic resolution

The biocatalyzed hydrolytic kinetic resolution of 2-, 3-, and 4-pyridyloxirane by the Aspergillus niger epoxide hydrolase (EH) has been explored. This was used to perform a gram scale preparation of these epoxides of (S) absolute configuration using a process performed at a concentration as high as 10 g/L (82 mM). All three epoxides have been obtained in a nearly enantiopure form (ee > 98%). Interestingly, it was shown that this biotransformation could be achieved using plain water instead of buffer solution, an important improvement as far as downstream processing of an eventual industrial process is concerned. Neither of these substrates could be obtained in reasonable enantiomeric purity and yield using the nowadays most efficient metal-based catalysts.