406188-98-5

Usage

Uses

Used in Pharmaceutical Industry:
(4'-TrifluoroMethylbiphenyl-4-yl)acetic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, including the trifluoromethyl group, may provide increased hydrophobicity and stability, which are desirable properties for drug development and design.
Used in Agrochemical Industry:
In the agrochemical industry, (4'-TrifluoroMethylbiphenyl-4-yl)acetic acid is used as a building block for the creation of novel agrochemicals. Its properties may contribute to the development of more effective and stable pesticides or other agricultural products.
Used in Materials Science:
(4'-TrifluoroMethylbiphenyl-4-yl)acetic acid is used as a component in the development of new materials with specific properties. The trifluoromethyl group can enhance the compound's performance in various applications, such as in the creation of high-performance polymers or coatings.

Upstream product

• 871252-44-7 2-(4'-(trifluoromethyl)biphenyl-4-yl)acetonitrile 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 

Relevant academic research and scientific papers

THIAZOLOPIPERAZINE DERIVATIVES AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES COMPRISING THE SAME

The present invention provides a thiazolopiperazine derivative, and a pharmaceutical composition and a health functional food composition for preventing or treating autoimmune diseases containing the same as an active component. A compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof according to the present invention can have an effect of inhibiting lysophosphatidic acid 1 (LPA1) receptor activation, thereby being able to be usefully used as the pharmaceutical composition or the health functional food composition for preventing or treating LPA1-related diseases. In addition, it is possible to effectively prevent or treat not only autoimmune diseases, but also other immune-related diseases with similar mechanisms of occurrence by using the pharmaceutical composition and the health functional food composition.COPYRIGHT KIPO 2020

GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES

The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like.

Compounds that modulate PPAR activity and methods for their preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.