40643-68-3Relevant academic research and scientific papers
Stereochemical preference of yeast epoxide hydrolase for the O-axial C3 epimers of 1-oxaspiro[2.5]octanes
Weijers, Carel A. G. M.,Koenst, Paul M.,Franssen, Maurice C. R.,Sudhoelter, Ernst J. R.
, p. 3106 - 3114 (2008/04/01)
The 1-oxaspiro[2.5]octane moiety is a common motif in many biologically active spiroepoxide compounds. Stereochemistry plays an important role in the action of these spiroepoxides, since the O-axial C3 epimers are predominantly responsible for biological
