40649-71-6 Usage
Uses
Used in Pharmaceutical Industry:
5-iodohistidine is used as a pharmaceutical compound for its potential therapeutic applications. The presence of the iodine atom in the molecule may contribute to its ability to modulate biological processes and target specific receptors or enzymes, making it a promising candidate for the development of new drugs.
Used in Diagnostic Imaging:
In the field of diagnostic imaging, 5-iodohistidine can be utilized as a contrast agent, particularly in medical imaging techniques such as X-ray computed tomography (CT) and magnetic resonance imaging (MRI). The iodine atom in the molecule enhances the visibility of tissues and organs, allowing for more accurate diagnosis and monitoring of various conditions.
Used in Research and Development:
5-iodohistidine serves as an important research tool in the field of biochemistry and molecular biology. It can be used to study the role of histidine in various biological processes, as well as to investigate the effects of iodine substitution on the structure and function of proteins and peptides.
Used in Radiopharmaceuticals:
In the development of radiopharmaceuticals, 5-iodohistidine can be employed as a precursor for the synthesis of radiolabeled compounds. The radiolabeled 5-iodohistidine derivatives can be used for targeted imaging and therapy of specific diseases, such as cancer, by taking advantage of the unique properties of the iodine atom.
Used in Nutritional Supplements:
5-iodohistidine may also find applications in the nutritional supplement industry, where it can be used to enhance the bioavailability and absorption of essential nutrients. The presence of the iodine atom in the molecule may improve the overall nutritional value of the supplement, contributing to better health and well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 40649-71-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,6,4 and 9 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 40649-71:
(7*4)+(6*0)+(5*6)+(4*4)+(3*9)+(2*7)+(1*1)=116
116 % 10 = 6
So 40649-71-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H8IN3O2/c7-5-4(9-2-10-5)1-3(8)6(11)12/h2-3H,1,8H2,(H,9,10)(H,11,12)/t3-/m0/s1
40649-71-6Relevant academic research and scientific papers
Proprietes physico-chimiques des iodohistidines. I. Etude protometrique de la complexation des cations metalliques Cu(II), Co(II), Ni(II), Cd(II), Zn(II) par la mono- et la diiodohistidine
Wang, Jide,Collange, Edmond,Aymes, Daniel J,Paris, Michel R,Fournaise, Robert
, p. 30 - 36 (2007/10/02)
Physicochemical properties of iodo-histidines.I.Protometric study of the complexation of metallic cations Cu(II), Co(II), Ni(II), Cd(II), Zn(II) by mono- and diiodohistidine.Mono- (MIH) et diiodo- (DIH) histidines are synthesized by iodination of histidine using ICl; their protonation contants are determined at 25 deg C in 0,5 mol*L-1 NaNO3 (or NaCl) together with the stability constants of their complexes formed with ions of the first transition series.Computer refinement of the stability constant values was done by adjusting the calculated and experimental curves of neutralization by the PROTAF program.This work provides evidence for a variety of complexes.Apart from simple complexes, such as MA and MA2, other protonated or deprotonated species, like MHA and MH2A or MH-1A and MH-2A, were formed depending on the system. histidine / monoiodohistidine /diiodohistidine / cobalt / complexes / protometry
