40657-29-2

Upstream product

• 40657-28-1 4,4-diethoxy-1,1-difluoro-1-nitro-2-trifluoromethyl-but-3-en-2-ol 
• 78-39-7 Triethyl orthoacetate 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 128648-63-5 (E)-4-anilino-4-ethoxy-1,1,1-trifluorobut-3-en-2-one 
• 128648-76-0 1,1,1-Trifluoro-4,4-bis-methylamino-but-3-en-2-one 
• 782-55-8 2-(trifluoroacetonyl)benzimidazole 
• 898539-91-8 (E)-4-(4-aminoanilino)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one 
• 898539-93-0 (E)-4-ethoxy-1,1,1-trifluoro-4-(4-nitroanilino)but-3-en-2-one 
• 898539-92-9 (E)-4-(4-acetylanilino)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one 
• 898539-90-7 (E)-4-(benzylamino)-4-ethoxy-1,1,1-trifluorobut-3-en-2-one 
• 510716-34-4 5-ethoxy-2-methyl-3-phenyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine 
• 1189142-24-2 2-(4-chlorophenyl)-5-ethoxy-7-trifluoromethylpyrazolo[1,5-a]pyrimidine 
• 404839-60-7 methyl 2-hydroxy-4-ethoxy-6-(trifluoromethyl)benzoate 
• 1162665-09-9 methyl 2-hydroxy-4-ethoxy-3methoxy-6-(trifluoromethyl)-benzoate 
• 122431-37-2 2-methyl-5-trifluoromethyl-2H-pyrazol-3-ol 
• 128648-65-7 (E)-4-Ethoxy-1,1,1-trifluoro-4-(4-methoxy-phenylamino)-but-3-en-2-one 

Relevant academic research and scientific papers

Synthesis of 6-(trifluoromethyl)-8,13,13d-triazadibenzochrysenes

Trifluoroacetyl ketene diethylacetal reacts thermally with 2-(2'-aminoaryl)perimidines 2 in diphenyl ether to give 6-(trifluoromethyl)-8,13,13d-triazadibenzochrysenes 4. - Keywords: Synthesis; Trifluoromethyl triazadibenzo-chrysenes; NMR spectroscopy; IR spectroscopy; Mass spectrometry

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

PYRAZOLE-SUBSTITUTED PYRROLIDINONES AS HERBICIDES

Disclosed are compounds of Formula (1), including all stereoisomers, N-oxides, and salts thereof, wherein Q is selected from the group consisting of and R1, R2, R3, Y, R4, R5, n, R6, W and

SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME

ABSTRACT The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.

Synthesis of trifluoromethyl-substituted arenes, cyclohexenones and pyran-4-ones by cyclocondensation of 1,3-bis(silyloxy)-1,3-butadienes with 4,4-dimethoxy-1,1,1-trifluorobut-3-en-2-one: Influence of the Lewis acid on the product distribution

(Chemical Equation Presented) The TiCl4-mediated formal [3 + 3] cyclocondensation of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with 4,4-dimethoxy-1,1,1-trifluorobut-3-en-2-one afforded a variety of functionalized 4-methoxy-6-(trifluoromethyl) s

SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS

Disclosed are compounds active against soluble epoxide hydrolase (sEH), compositions thereof and methods of using and making same.

A Useful One-Step Synthesis of β-Trihaloacetylvinyl Ethers and Trihaloacetylketene Acetals

Trifluoro- and trichloroacetylation of ethyl orthoacetate and some methyl ketone acetals affords the corresponding acylketene acetals and α-substituted β-acylvinyl ethers, respectively, in high yields.