40662-09-7Relevant academic research and scientific papers
A General Strategy for Visible-Light Decaging Based on the Quinone Trimethyl Lock
Walton, David P.,Dougherty, Dennis A.
, p. 4655 - 4658 (2017)
Visible-light triggered quinone trimethyl locks are reported as a general design for long-wavelength photoremovable protecting groups for alcohols and amines. Intramolecular photoreduction unmasks a reactive phenol that undergoes fast lactonization to release alcohols and amines. Model substrates are released in quantitative yield along with well-defined, colorless hydroquinone byproducts. Substituent modifications of the quinone core allow absorption from 400 to 600 nm.
