406699-89-6

Usage

Structure

A quinolinone ring with an acetyl group at the 8th position, a hydroxy group at the 7th position, and a methyl group at the 4th position.

Derivative of quinolinone

Yes

Potential biological activities

Antiviral, antibacterial, and anticancer properties

Potential pharmacological properties

Therapeutic applications in drug development

Need for further research

Yes

Upstream product

• 362519-02-6 4,8,9-trimethylfuro[2,3-h]quinolin-2(1H)-one 
• 20513-71-7 7-hydroxy-4-methylquinolin-2(1H)-one 
• 354130-49-7 4-methyl-2-oxo-1,2-dihydroquinolin-7-yl acetate 

Relevant academic research and scientific papers

Synthesis, photooxygenation, and characterization of new angular furoquinolinone derivatives, a new furocoumarin bioisoster

Synthesis of angular furoquinolinone derivatives with a new skeleton structure was accomplished via Williamson reaction of hydroxyquinolinones with α-haloketones, such as 3-chloro-2-butanone and phenacyl bromide, followed by treatment with polyphosphoric

New syntheses of furoquinoline derivatives

Fries rearrangement of 7-acyloxyquinolin-2-one and 7-acyloxy-2- chloroquinoline derivatives and their analogs provides useful intermediates for new ways of furoquinoline derivatives syntheses.