406719-77-5 Usage
Uses
Used in Pharmaceutical Industry:
2-Thiophenecarboxylic acid, 4-cyano-(9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Industry:
In the chemical industry, 2-Thiophenecarboxylic acid, 4-cyano-(9CI) is used as a precursor for the synthesis of other organic compounds. Its reactivity and functional groups make it a valuable component in the production of various chemical products.
Used in Organic Chemistry Research:
2-Thiophenecarboxylic acid, 4-cyano-(9CI) is used as a subject of study in organic chemistry research. Its unique structure and properties provide opportunities for exploring new reactions, mechanisms, and applications, contributing to the advancement of organic chemistry knowledge.
Used in Drug Development:
2-Thiophenecarboxylic acid, 4-cyano-(9CI) has potential biological activities, making it a promising candidate for drug development. It can be used as a starting material for the design and synthesis of new drugs with potential therapeutic effects.
Used in Material Science:
The unique structure and properties of 2-Thiophenecarboxylic acid, 4-cyano-(9CI) also make it a candidate for the development of new materials with specific properties. It can be used in the synthesis of polymers, coatings, or other materials with desired characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 406719-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,6,7,1 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 406719-77:
(8*4)+(7*0)+(6*6)+(5*7)+(4*1)+(3*9)+(2*7)+(1*7)=155
155 % 10 = 5
So 406719-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H3NO2S/c7-2-4-1-5(6(8)9)10-3-4/h1,3H,(H,8,9)
406719-77-5Relevant academic research and scientific papers
Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
Zhang, Penglie,Huang, Wenrong,Wang, Lingyan,Bao, Liang,Jia, Zhaozhong J.,Bauer, Shawn M.,Goldman, Erick A.,Probst, Gary D.,Song, Yonghong,Su, Ting,Fan, Jingmei,Wu, Yanhong,Li, Wenhao,Woolfrey, John,Sinha, Uma,Wong, Paul W.,Edwards, Susan T.,Arfsten, Ann E.,Clizbe, Lane A.,Kanter, James,Pandey, Anjali,Park, Gary,Hutchaleelaha, Athiwat,Lambing, Joseph L.,Hollenbach, Stanley J.,Scarborough, Robert M.,Zhu, Bing-Yan
scheme or table, p. 2179 - 2185 (2009/12/07)
Systematic SAR studies of in vitro factor Xa inhibitory activity around compound 1 were performed by modifying each of the three phenyl rings. A class of highly potent, selective, efficacious and orally bioavailable direct factor Xa inhibitors was discovered. These compounds were screened in hERG binding assays to examine the effects of substitution groups on the hERG channel affinity. From the leading compounds, betrixaban (compound 11, PRT054021) has been selected as the clinical candidate for development.
