406720-98-7Relevant academic research and scientific papers
Palladium-catalyzed nucleophilic substitution of propargylic carbonates and meldrum's acid derivatives
Ambrogio, Ilaria,Cacchi, Sandro,Fabrizi, Giancarlo,Goggiamani, Antonella,Iazzetti, Antonia
, p. 3147 - 3151 (2015/05/13)
The palladium-catalyzed reaction of propargylic carbonates with Meldrum's acid derivatives proceeds smoothly in the presence of Pd(OAc)2 and P(2-furyl)3 in THF at 80 °C to give substitution products. The substitution products can be
Palladium-catalyzed synthesis of 2-amino ketones from propargylic carbonates and secondary amines
Cacchi, Sandro,Fabrizi, Giancarlo,Filisti, Eleonora,Goggiamani, Antonella,Iazzetti, Antonia,Maurone, Loredana
, p. 4699 - 4703 (2012/08/08)
A novel palladium-catalyzed approach to 2-amino ketones from arylpropargylic carbonates bearing neutral, electron-rich, and electron-poor aromatic rings and cyclic secondary amines containing useful functional groups such as cyano, chloro, and bromo subst
Titanium/palladium-mediated regioselective propargylation of ketones using propargylic carbonates as pronucleophiles
Millan, Alba,De Cienfuegos, Luis Alvarez,Martin-Lasanta, Ana,Campana, Araceli G.,Cuerva, Juan M.
supporting information; experimental part, p. 73 - 78 (2011/04/12)
An efficient protocol for the synthesis of homopropargylic alcohols using propargylic carbonates as pronucleophiles is reported. The reaction is based on a combination of transition metal (palladium) and radical chemistry (titanium). The reaction takes pl
