40682-75-5Relevant academic research and scientific papers
A convenient synthesis of secondary hydroxylamines
O'Neil, Ian A.,Cleator, Ed,Tapolczay, David J.
, p. 8247 - 8249 (2001)
The oxidation of a range of β-cyanoethyl tertiary amines with mCPBA gives the corresponding N-oxides, which can be isolated or undergo Cope-elimination to give secondary hydroxylamines in excellent yield.
The synthesis and structure of chiral enamine N-oxides
O'Neil,McConville,Zhou,Brooke,Robertson,Berry
, p. 7336 - 7339 (2014)
Chiral enamine N-oxides have been synthesised by a diastereoselective intermolecular reverse-Cope cycloaddition reaction between chiral hydroxylamines and activated acetylenes. Their structures have been investigated by NMR, X-ray crystallography and computational methods.
The synthesis of highly functionalized morpholine N-oxides from ephedrine and pseudoephedrine utilizing a tandem Cope elimination/reverse Cope elimination protocol
Henry, Neil,O'Neil, Ian A.
, p. 1691 - 1694 (2008/02/05)
Highly functionalized monocyclic morpholine N-oxides can be prepared in three steps starting from ephedrine and pseudoephedrine utlizing a tandem Cope elimination/reverse Cope elimination.
