40683-91-8

Upstream product

• 22699-63-4 N,N-dicyclohexylformamide 
• 143-33-9 sodium cyanide 
• 101-83-7 N-cyclohexyl-cyclohexanamine 
• 506-68-3 bromocyane 

Downstream Products

• 40683-87-2 N¹,N¹-Dicyclohexyl-N²-(dichlorthiophosphoryl)-chlorformamidin 
• 22080-48-4 tetra-N-cyclohexyl-2-ethyl-2-thioxo-2H-2λ⁵-[1,3,5,2]thiadiazaphosphinine-4,6-diamine 
• 15134-53-9 (CO)5Cr{NCN(C₆H₁₁)2} 
• 94380-05-9 N,N,O-Tricyclohexyl-isoharnstoff 

Relevant academic research and scientific papers

Selective Gold-Catalysed Synthesis of Cyanamides and 1-Substituted 1H-Tetrazol-5-Amines from Isocyanides

The newly discovered gold-catalysed reaction of isocyanides with hydrazoic acid generated in situ from trimethylsilyl azide and methanol (or, alternatively, from NaN3/AcOH) produces either cyanamides or 1-substituted 1H-tetrazol-5-amines, depending on the amount of available HN3. The reaction proceeds selectively and in generally high yields of either product, thus providing a particularly convenient access to a wide range of substituted 1H-tetrazol-5-amines that are rather difficult to access otherwise.

A copper-mediated oxidative N-cyanation reaction

Copper-promoted N-cyanation of aliphatic sec-amine by CuCN is achieved via oxidative coupling. This procedure employs O2 as a clean oxidant. Notably, sulfoximines and 1,1,3,3-tetramethylguanidine also worked well in this procedure. Thus, it represents a key progress in the C-N bond formation reaction as well as in the cyanation reaction. This journal is the Partner Organisations 2014.

1-CYANOBENZOTRIAZOLE: A SAFE AND CONVENIENT SOURCE OF (+)CN

Readily available 1-cyanobenzotriazole is a convenient reagent for the conversion of secondary amines into the corresponding cyanamides. Exploratory work with primary amines and with mercaptans is also reported.