406937-95-9

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 100132-60-3 (S)-2-(toluene-4-sulfonamido)propan-1-ol 
• 88129-44-6 (S)-N-(p-toluenesulfonyl)-2-amino-1-propyl p-toluenesulfonate 
• 4816-81-3 p-tosyl-L-alanine 
• 7342-82-7 3-Bromothianaphthene 
• 119461-40-4 S-(+)-2-methyl-N-p-tosylaziridine 

Downstream Products

• 406938-17-8 N-(2-benzo[b]thiophen-3-yl-1-methyl-ethyl)-4,N-dimethyl-benzenesulfonamide 

Relevant academic research and scientific papers

A new convenient approach to chiral β-aryl(heteroaryl)alkylamines

Chiral β-aryl(heteroaryl)alkylamines have been prepared from N-tosyl alkylaziridines via regiospecific nucleophilic ring opening and subsequent desulfonylation in good to excellent yields. The corresponding aziridines are easily obtained from commercially available (S)-α-amino acids, so this method is the first effective route to asymmetric β-aryl(heteroaryl)alkylamines.