4073-80-7

Upstream product

• 22118-09-8 2-bromoacetyl chloride 
• 101-84-8 diphenylether 
• 2615-11-4 4,4'-oxydiacetophenone 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 2489-92-1 4,4'-bis(phenylglyoxalyl) ether 
• 1251195-93-3 (S)-5,5'-(4,4'-oxybis(4,1-phenylene))bis(2-((S)-pyrrolidin-2-yl)-1H-imidazole) 
• 1256383-69-3 dimethyl ((2S,2'S)-((2S,2'S)-2,2'-(5,5'-(oxybis(4,1-phenylene))bis(1H-imidazole5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl))dicarbamate 
• 1240427-94-4 (2S,2'S)-tert-butyl 2,2'-(5,5'-(4,4'-oxybis(4,1-phenylene))bis(1H-imidazole-5,2-diyl))dipyrro lidine-1-carboxylate 
• 1240427-81-9 (2S,2'S)-1-tert-butyl '2,2-2,2'-(4,4'-oxybis(4,1-phenylene))bis(2-oxo-ethane-2,1-diyl)dipyrrolidine-1,2-dicarboxylate 
• 34838-63-6 2-(Triphenyl-λ⁵-phosphanylidene)-1-(4-{4-[2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-phenoxy}-phenyl)-ethanone 
• 7477-88-5 bis-{4-[(2-chloro-pyridinio)-acetyl]-phenyl}-ether ; dibromide 

Relevant academic research and scientific papers

POTENT AND SELECTIVE INHIBITORS OF HEPATITIS C VIRUS

The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as also pharmaceutically acceptable, salts, prodrugs, and othe

Synthesis and biological evaluation of new potent and selective HCV NS5A inhibitors

NS5A inhibitors are a new class of direct-acting antiviral agents which display very potent anti-HCV activity in vitro and in humans. Rationally designed modifications to the central biphenyl linkage of a known NS5A series led to selection of several comp

ANTIVIRAL COMPOUNDS

The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

The 'inverse electron-demand' Diels-Alder reaction in polymer synthesis. Part 2. Some bis(1,2,4-triazines) as potential bis-diene monomers

Synthetic approaches to a series of 5,5'-linked bis(1,2,4-triazines) are described: these are potential monomers in Diels-Alder polymerisation processes.Oxidation of bis(α-bromophenylacetyl) substituted aromatic compounds with dimethyl sulfoxide, or (better) oxidation of diacetyl- or bis(phenylacetyl) substituted aromatic compounds with hydrogen bromide in dimethyl sulfoxide, gives the corresponding bis(1,2-diketones) and bis(α-keto aldehydes); these are converted into 3,3'-bis(methylsulfanyl)-5,5'-arylenebis(1,2,4-triazines) by reaction with S-methylthiosemicarbazide.The methylsulfanyl groups may then be oxidised by standard methods to give the corresponding methylsulfinyl or methylsulfonyl compounds, although the oxidised products show a tendency to decompose on storage.