40732-48-7

Basic information

• Product Name: GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
• Synonyms: guanosine-3’,5’-cyclicmonophosphate(cgmp),sodiumsalt;CGMP SODIUM SALT;CGMP NA;CYCLIC GMP SODIUM SALT;GUANOSINE 3',5'-CYCLOPHOSPHATE MONOSODIUM SALT;GUANOSINE 3',5'-MONOPHOSPHATE MONOSODIUM SALT;GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT;GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
• CAS NO: 40732-48-7
• Molecular Formula: C10H11N5NaO7P
• Molecular Weight: 367.19
• EINECS: 255-056-0
• Mol File: 40732-48-7.mol
• Article Data: 0

Chemical Properties

• Appearance: white/powder
• Storage Temp.: −20°C
• Solubility: H2O: 50 mg/mL
• BRN: 6467425
• CAS DataBase Reference: GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT(40732-48-7)
• EPA Substance Registry System: GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT(40732-48-7)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 40732-48-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Guanosine 3’,5’-Cyclic Monophosphate is a substituted Guanosine having cyclic phosphodiesterase activity.

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).